**4.4. Application in the medical field**

A body or an organism can be subjected to the action of several harmful external factors, such as: radiation flow (ultraviolet, thermal, neutrons, X-ray, etc.), viruses, stresses, etc. The total effects of the cumulative action of a viruses, a radiation, stress and a pollutant upon an organism, or upon a particular cell, may be obtained by calculating the total participation of the specific energies,

$$P\_t\left(t\right) = \left(\frac{m\_v}{m\_{v,cr}}\right)^{a\_v + 1} + \left(\frac{\mathfrak{O}}{\mathfrak{O}\_{cr}}\right)^{a\_\Phi + 1} + \left(\frac{\mathfrak{S}}{\mathfrak{S}\_{cr}}\right)^{a\_\mathcal{S} + 1} + \left(\frac{c}{c\_\alpha}\right)^{a\_\iota + 1} \tag{39}$$

where *mv* and *mv*,*cr* is the 'quantity' of a certain virus and its critical values; Φ and Φ*cr* is the certain radiation flow and its critical value; *S* and *Scr* is the stress produced upon the organism and its critical value; *c* and *ccr* is the concentration and its critical value of a certain pollutant. The exponents α*v*, αΦ, α*S* and α*c* have the meaning of α*<sup>i</sup>* from Eq. (12). That means the virus behaviour, the radiation flow behaviour, the stress behaviour and the pollutant behaviour are nonlinear and are described by general law (6).

If they are more external action for each category the total participation is:

$$P\_T\left(t\right) = \sum\_{i} \left(\frac{m\_{v,i}}{\left(m\_{v,i}\right)\_{cv}}\right)^{a\_{v\_i} \cdot 1} + \sum\_{j} \left(\frac{\Phi\_{j}}{\Phi\_{j,cv}}\right)^{a\_{v\_j} \cdot 1} + \sum\_{k} \left(\frac{S\_k}{S\_{k,cr}}\right)^{a\_{v\_k} \cdot 1} + \sum\_{l} \left(\frac{c\_l}{c\_{l,cr}}\right)^{a\_{v\_l} \cdot 1} \tag{40}$$

If *Pt* (*t*)<1 or *PT* (*t*)<1 the critical state is not attained, whereas if *Pt* ≥1 of *PT* (*t*)≥1 the critical state is reached or exceeded (the organism dies).

The critical participation contains deterioration of the living body and the weakness due to lack of vitamins, oligoelements, etc. *Wn*, such as:

$$P\_{cr}\left(t\right) = 1 - D\left(t\right) - \sum\_{n} W\_{n} \tag{41}$$

If *PT* (*t*)< *Pcr* (*t*), the critical state is not attained.

In order to help the organism to survive, or to get beyond the state of temporary illness, one administrates a quantity of medication *m*, whose critical value is *mcr*. The medication partici‐ pations opposes the weakness, such as,

$$P\_{cr}\left(t\right) = 1 - D\left(t\right) - \sum\_{n} W\_{n} + \left(\frac{m}{m\_{cr}}\right)^{a\_{n} + 1} \tag{42}$$

can be higher the unity.

The total participation thus calculated is compared to the critical participation,

where *DT* (−*t*) previously produced deterioration (−*t*) upon the biophysical factor.

(*t*) the status of the biophysical factor is subcritical, while if *PT* (*cp*) ≥*Pcr*

Proceedings of the International Conference on Interdisciplinary Studies (ICIS 2016) - Interdisciplinarity and Creativity

Sometimes the interaction of pollutants from a mixture produces a change in their behaviour, as they mutually enhance their obnoxious effects. One can get a positive synergistic effect, meaning that the effect of the mixture is greater than the sum of the individual effects of the pollutants [14]. Positive synergism does not mean that one can get more out of 'something plus something else', but it means that the behaviour of that 'something' changes in the presence of the 'something else' which makes the whole effect be greater than the sum of the composing

A body or an organism can be subjected to the action of several harmful external factors, such as: radiation flow (ultraviolet, thermal, neutrons, X-ray, etc.), viruses, stresses, etc. The total effects of the cumulative action of a viruses, a radiation, stress and a pollutant upon an organism, or upon a particular cell, may be obtained by calculating the total participation of

( ) <sup>Φ</sup> α 1 α 1 α1 α1

*v cr cr cr cr*

where *mv* and *mv*,*cr* is the 'quantity' of a certain virus and its critical values; Φ and Φ*cr* is the certain radiation flow and its critical value; *S* and *Scr* is the stress produced upon the organism and its critical value; *c* and *ccr* is the concentration and its critical value of a certain pollutant.

behaviour, the radiation flow behaviour, the stress behaviour and the pollutant behaviour are

, , ,,

*i j kl v i j cr k cr l cr cr*

= + ++ ç ÷ ç ÷ ç ÷ ç÷ ç ÷ ç ÷ Fè ø è ø èø è ø

aF

*m S c*

*v i j k l*

<sup>+</sup> <sup>+</sup> <sup>+</sup> <sup>+</sup> æ ö æ ö F æ ö æö

<sup>1</sup> <sup>1</sup> <sup>1</sup> <sup>1</sup>

å å åå (40)

a

*<sup>S</sup> <sup>v</sup> <sup>k</sup> <sup>i</sup> <sup>j</sup> cl*

*v S c*

Φ Φ

*<sup>m</sup> S c P t m S c* <sup>+</sup> + ++ æ ö æ ö æö æö = + ++ ç ÷ ç ÷ ç÷ ç÷ ç ÷ è ø è ø èø èø

If they are more external action for each category the total participation is:

*<sup>m</sup> S c P t*

,

The exponents α*v*, αΦ, α*S* and α*c* have the meaning of α*<sup>i</sup>*

a

nonlinear and are described by general law (6).

,

( ) ( )

*T*

*v*

If *PT* (*cp*) <*Pcr*

effects!

the specific energies,

is critical or supercritical.

in the Knowledge Society

16

**4.4. Application in the medical field**

*t*

*Pt D t cr* ( ) =- - 1 *<sup>T</sup>* ( ) (38)

(*t*) —the state

(39)

from Eq. (12). That means the virus

a

If more useful medication will be administered,

$$P\_{cr}\left(t\right) = 1 - D\left(t\right) - \sum\_{n} W\_{n} + \sum\_{p} \left(\frac{m\_{p}}{m\_{p,cr}}\right)^{\alpha\_{n,p} \cdot 1} \tag{43}$$
