**3. Conclusions**

Conclusively, intensive review of enzyme activities has revealed the significance of indigenous milk enzymes with varied concentration behavior during lactation stages. Lactation stage has a prominent effect on enzymes activities and ultimately it may affect the technological behavior of milk composition.

Generally, colostrum formation contains higher enzyme activities than during the established lactation period. Mastitis or several other progressions that increase leukocytes in milk increase enzyme activities such as CAT. LP, ACP, and LP decrease while lipase activity increases with progress of lactation. ALP activity first increases then decreases at the end of lactation. PL activity increases in the late lactation because of that it makes milk less suitable for cheese making.

This varied behavior of enzyme activities at early, mid, and late lactation stages can be a troubling problem for manufacturing of milk and milk products in various regions of the world. As enormous animals in late lactation periods and considerable seasonal variations affect the ultimate quality of milk and have a better increased choice to process the specified valued dairy product. Furthermore, milk from mid lactation would be a balanced source of energy to maintain the health status of the individuals.
