**Delivery Systems in Wound Healing and Nanomedicine Delivery Systems in Wound Healing and Nanomedicine**

Lina Fu Lina Fu

Additional information is available at the end of the chapter Additional information is available at the end of the chapter

http://dx.doi.org/10.5772/63763

### **Abstract**

Introduction: Delivery systems in nanomedicine contribute to the improvements in wound healing, tissue regeneration, and anticancer pharmacological fields. Although various wound dressings have been used in wound care treatments, there is a great challenge in the wound management of ulcers, trauma, chronic wounds, and severe injury and burns, especially infected wounds.

Body: To accelerate wound healing, influence tissue repair, reduce scarring, and control infection, various delivery devices have been developed in wound healing. The application of delivery devices has improved early as well as long‐term wound care in delayed healing wounds. Main delivery systems are described, including drugs, bioactive proteins/growth factors, genes, and cells, outlining the advantages and limitations of each carrier in wound healing, as well as the mechanisms and release. This chapter reviews biomaterials and scaffolds that provide the carriers of bioactive agents, which include antimicrobial agents, combinations of cells, growth factors and genes, both scaffolds and cell interactions toward regeneration of skin tissues, vascular reconstructions, as well as transdermal carriers. In addition, the regulations, procedures, and clinical trails for delivery systems for wound healing are discussed.

Conclusion: In the past decades, many wound dressings and skin substitutes have been developed to treat skin loss and wounds. Delivery systems can improve wound healing and tissue regeneration. Looking toward the future, the need for delivery wound healing products for chronic and complex wounds will increase. Functionalized delivery systems will probably be the academic interest and industrial focus on wound healing.

**Keywords:** wound healing, delivery system, wound dressing, skin regeneration, bio‐ materials

© 2016 The Author(s). Licensee InTech. This chapter is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. © 2016 The Author(s). Licensee InTech. This chapter is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
