**2. Understanding tissue healing**

Understanding tissue healing is fundamental in wound management. Such a complex physiological process is proven to be dependent on multiple inter-related factors [2].

Wound healing can be defined as the process by which the body restores and replaces function to damaged tissues [3]. Following tissue trauma, healing can be initiated through one of the two mechanisms:

1. Regeneration, which means replacement of damaged tissue by an identical type of tissue. This process is only confined to a few types of cells, for example epithelial, liver and nerve cells [2].

2. Repair, where damaged tissues are replaced by connective tissue to form a scar. This mechanism occurs in vast majority of cases [2].
