**8. Conclusion**

Managing chronic and refractory wounds represents a significant dilemma that physicians are facing and needs invention of new treatment modalities. Wide ranges of the above physical modalities have been introduced and used in wound‐healing treatment with different efficacies, but most of them, to some extent, are strange for patients and physicians. Although additional clinical studies must be performed in order to find out the best modalities and the best parameters of wavelength, dosage, and methodology, and especially appropriate treat‐ ment protocols, we think these modalities need more attention to be paid and should be kept in mind for treating persistent ulcers.
