*3.8.3. Usage in Raynaud's phenomenon*

IRT was initially tested in 1991 for the diagnosis of Raynaud's phenomenon to determine temperature differences, which is one of the pathognomonic signs of this phenomenon [37]. In 1998, von Bierbrauer. et al reported that DITI is a useful tool in the diagnosis of Raynaud's phenomenon in vibration-induced white finger, which is an occupational disease and is triggered by vibration and/or cold exposure [40].
