**Meet the editor**

Jan Oxholm Gordeladze, PhD (born on the 25th of April, 1950), holds a triple professor competence (medical biochemistry, physiology, and pharmacology) and is presently working as a professor at the Inst. of Basic Medical Science, Dept. for Molecular Medicine, Section for Biochemistry, University of Oslo, Norway. He has previously been employed as the medical director of Merck Sharp &

Dohme (MSD), Norway, serving two years as a Fulbright scholar at the NIH, Bethesda, Maryland, USA, and from 2006 to 2009, he has been employed as associate professor at the University of Montpellier, France. He has published more than 130 scientific articles and reviews/book chapters and presented more than 260 abstracts/posters/talks at conferences worldwide. At present, he and his research team are focused on research related to stem cell differentiation, cell phenotype stabilization by manipulating regulatory looping systems consisting of key genes and microRNAs, as well as the impact of vitamin K2 on cellular and organ functions, including osteoblasts (bone), chondrocytes (cartilage), striated muscle cells (skeletal muscle), and adipocytes (white and brown fat tissues).

Contents

**Preface IX**

Chapter 1 **Introductory Chapter: Vitamin K2 3** Jan Oxholm Gordeladze

Kotaro Azuma and Satoshi Inoue

**Section 2 Vitamnin K2 Rich Food – Impact of K2 on Energy**

Chapter 4 **Menaquinones, Bacteria, and Foods: Vitamin K2 in**

Chapter 5 **The Impact of Vitamin K2 on Energy Metabolism 83**

**Section 3 The Impact of Vitamnin K2 on Bones and Teeth 99**

Niels Erik Frandsen and Jan Oxholm Gordeladze

Håvard Jostein Haugen and Harald Osmundsen

Chapter 7 **Vitamin K2 and its Impact on Tooth Epigenetics 125**

Barbara Walther and Magali Chollet

Muhammad Yasin, Masood Sadiq Butt and Aurang Zeb

Mona Møller, Serena Tonstad, Tone Bathen and Jan Oxholm

Jan Oxholm Gordeladze, Maria A. Landin, Gaute Floer Johnsen,

Chapter 2 **Vitamin K, SXR, and GGCX 21**

**Metabolism 33**

**the Diet 63**

Gordeladze

Chapter 6 **Vitamin K2 and Bone Health 101**

Chapter 3 **Vitamin K2 Rich Food Products 35**

**Section 1 Introduction 1**
