**8. Conclusions**

The inflammatory process seen in MS is due to an excess production of pro‐inflammatory cytokines, which leads to increased secretion of ROS. Oxidative stress plays a preponderant, key role in the pathogenesis of MS. Reactive oxygen species generated by macrophages have been implicated as mediators of demyelination and axonal damage in EAE and MS. The main findings of a clinical trial conducted with relapsing‐remitting MS patients who received a diet supplemented with 4 g/day of fish oil or olive oil are the following:

