*4.1.2. Quasispecies Reconstruction algorithm (QuRe)*

Principle: QuRe [74] is based on a heuristic algorithm and automatically reconstructs a set of error-free, full-gene/genome variants from a collection of long NGS reads (>100 bp).

#### Algorithm steps:


**vi.** Reconstruction of quasispecies is carried out using the sliding window approach by calculating maximal coverage and read diversity, which reduces the false positives, *i.e.*, *in-silico* recombinants.
