**3.1. Next-generation sequencing platform performance**

Next-generation sequencing on the Illumina platform produced 13 690 589 (96.74%) reads that passed initial filtering. This process removes any clusters demonstrating excessive intensity corresponding to bases other than the called base. Only reads that passed the quality filter were assigned a quality score. A quality score of Q30 was accepted in the run predictive of an error probability of ≤0.1%. One sample was excluded from analysis due to poor DNA quality that generated poor-quality scores across all genomic regions.

Overall coverage across all genomic targets was 92.3%. This was consistent with the initial software prediction.
