**Acknowledgements**

Research of MAMR, ZH, OZ, VA and RK was financially supported by NANOSEMED KAN208130801. NAA and EP gratefully acknowledge the financial supports received from both FCT (Government of Portugal) through contract (SFRH/BPD/84671/2012) and from the Aveiro University Research Institute/CESAM (UID/AMB/50017/2013).
