**2. Rationale**

Globally, 5.0–7.0% of the general male population was affected by infertility and the trend may increase in the future, considering the apparent decline of sperm count in industrialized countries [4]. Male infertility, a multifactorial complex disease, has been a source of concern in India lately. Recent statistics reports that the percentage of male infertility has elevated to 60% now against 40% in 1980s (New Indian express, 2015). The magnitude of the problem calls for urgent action, particularly when the infertility is avoidable in the majority of cases.
