The oral glucose tolerance test was found to be of interest in patients with a negative fast test (Wiesli et al. 2004b) (Kar et al. 2006), but it was shown to be less accurate than the mixed meal test (Hogan et al. 1983) and is not recommended by the 2009 expert consensus (Cryer et al. 2009). 10% of healthy persons were reported to have a plasma glucose nadir less than 0.5 g/L during this test while being asymptomatic and without presenting with Whipple's triad (Lev-Ran & Anderson 1981). Whether such subjects may have some subtle abnormality regarding glucose regulation may still be debated, but this test was not considered as a tool to provide diagnostic evidence for a hypoglycaemic disorder.
