**5. Interaction of lipoxygenase with inhibitors as theoretical approach for food industry and medical applications**

In terms of the structure and function, LOXs are unique, because their metal cofactor is a single ion bound by the side chains of the surrounding amino acids and the carboxylic group of the C-terminus, and their inhibitors bind to or near the Fe co-factor (Skrzypczak-Jankun et al., 2007). Lipoxygenases are inhibited by a large number of chemicals, some of which also serve as co-substrates (Kulkarni, 2001).
