**Oxidative Stress in Cystic Fibrosis**

D. González Jiménez, J.J. Díaz Martín, R.P. Arias Llorente and C. Bousoño García

Additional information is available at the end of the chapter

http://dx.doi.org/10.5772/60661

### **Abstract**

Airway infection leads to progressive damage of the lungs in patients with cystic fibrosis (CF). Oxidative stress has been implicated as a causative factor in the aetiology of that process. Supplementation with antioxidant micronutrients (vitamin E, vitamin C, ß-carotene and selenium), docosahexaenoic acid or glutathione might therefore be helpful in maintaining an adequate redox balance. Current literature suggests a relationship between oxidative status and lung function. In this chapter we will summarize the main pathways of oxidative stress, focusing on results of new antioxidant treatments.

**Keywords:** Oxidative stress, fat-soluble vitamins, β-carotene, glutathione, essential fatty acid, antioxidants
