Contents

**Preface XIII**


#### X Contents

### **Section 3 Microbiology of Cystic Fibrosis 141**


### Chapter 15 **In vivo Gene Correction of Cystic Fibrosis 357** Michael Sebastian Daniel Kormann

**Section 3 Microbiology of Cystic Fibrosis 141**

**Section 4 CFTR - Mutations and Modifiers 199**

**Literature 143** Dennis Wat

**VI** Contents

Caroline Raynal

Chapter 7 **Respiratory Virus in Cystic Fibrosis — A Review of the**

**Biofilm Formation and Viability 171**

Chapter 9 **New Molecular Diagnosis Approaches — From the**

Chapter 10 **Emerging Roles of microRNAs in Cystic Fibrosis — From**

Chapter 11 **New Research on the Importance of Cystic Fibrosis**

Noel G. McElvaney and Emer P. Reeves

Chapter 12 **Role of Non-coding RNAs in Cystic Fibrosis 279**

Chapter 13 **Therapy for Cystic Fibrosis Caused by Nonsense**

**Section 5 Cystic Fibrosis: Genetic Correction 307**

Finotti and Monica Borgatti

**Therapy in the Airways 327**

**Mutations 309**

Sabrina Noel and Teresinha Leal

**Neutrophil Activity 249**

Chapter 8 **An Overview of Infections in Cystic Fibrosis Airways and the**

**Role of Environmental Conditions on Pseudomonas aeruginosa**

Cameron T. McDaniel, Warunya Panmanee and Daniel J. Hassett

**Identification of Mutations to their Characterization 201** Anne Bergougnoux, Magali Taulan-Cadars, Mireille Claustres and

**Pathogenesis to Development of New Therapies 233**

**Transmembrane Conductance Regulator Function for Optimal**

Michelle M. White, Fatma Gargoum, Niall Browne, Killian Hurley,

Roberto Gambari, Giulia Breveglieri, Francesca Salvatori, Alessia

Jessica Varilh, Jennifer Bonini and Magali Taulan-Cadars

Chapter 14 **Integrating Viral and Nonviral Vectors for Cystic Fibrosis Gene**

Ashley L Cooney, Paul B McCray, Jr and Patrick L. Sinn
