**Author details**

Ara Kaprelyan\*

Address all correspondence to: arakapri07@yahoo.co.uk

Department of neurology and neurosciences, "Prof. D-r P. Stoyanov" Medical University of Varna, Varna, Bulgaria

## **References**


[19] Kamimura D, Yamada M, Harada M, et al. The gateway theory: Bridging neural and immune interactions in the CNS. Front Neurosci, 2013; 7:204.

[5] Blinkenberg M, Jensen C, Holm S, Paulson O, Sørensen P. A longitudinal study of cerebral glucose metabolism, MRI, and disability in patients with MS. Neurology,

[6] Bolcaen J, Acou M, Mertens K, et al. Structural and metabolic features of two differ‐ ent variants of multiple sclerosis: A PET/MRI study. J Neuroimaging, 2013;

[7] Bybel B, Wu G, Brunken R, et al. PET and PET/CT imaging. Cleve Clin J Med, 2006;

[8] Chatzikonstantinou A, Szabo K, Ottomeyer C, et al. Successive affection bilateral temporomesial structures in a case of non-paraneoplastic limbic encephalitis demon‐

[9] Derache N, Marié R, Constans J, Defer G. Reduced thalamic and cerebellar rest me‐ tabolism in relapsing-remitting multiple sclerosis, a positron emission tomography

[10] Faria D, Copray S, Buchpiguel C, Dierckx R, de Vries E. PET imaging in multiple

[11] Fisher R, Patel N, Lai E, Schulz P. Two different 18F-FDG brain PET metabolic pat‐ terns in autoimmune limbic encephalitis. Clin Nucl Med, 2012; 37:213-218.

[12] Gajofatto A, Bongianni M, Zanusso G, et al. Clinical and biomarker assessment of de‐ myelinating events suggesting multiple sclerosis. Acta Neurol Scand, 2013; doi:

[13] Goverman J. Autoimmune T cell response in the central nervous system. Nature Re‐

[14] Haberlandt E, Bast T, Ebner A, et al. Limbic encephalitis in children and adolescents.

[15] Il'ves A, Prakhova L, Kataeva G, et al. Changes of cerebral glucose metabolism in pa‐ tients with multiple sclerosis and their role in formation of the clinical picture and progression of the disease. Zh Nevrol Psikhiatr Im S S Korsakova, 2003; 2:53-60. [16] Il'ves A, Prakhova L, Kataeva G, Petrov A, et al. Clinical and radiological (PET, MRI) correlations depending on disease progression in patients with multiple sclerosis. Zh

[17] Javdar H, Colleti P. Competitive advantage of PET/MRI. Eur J Rad, 2014, 83(1):84-94. [18] Kaira K, Okamura T, Takahashi H, et al. Small-cell lung cancer with voltage-gated calcium channel antibody-positive paraneoplastic limbic encephalitis: A case report. J

strated by serial MRI and FDG-PET. J Neurol, 2009; 256:1753-1755.

study: Correlations to lesion load. J Neurol Sci, 2006; 245(1-2):103-9.

sclerosis. J Neuroimm Pharm, 2014; 9(4):468-482.

views Immunol, 2009; 9(6):393. doi:10.1038/nri2550

Nevrol Psikhiatr Im S S Korsakova, 2006; 3:81-6.

1999; 53(1):149-53.

50 Immunopathology and Immunomodulation

23:431-436.

73:1075-1087.

10.1111/ane.12123.

Arch Dis Child, 2011; 96:186-191.

Med Case Rep, 2014; 8:119.


**Section 2**
