**4. Workplace Drug Testing (WDT)**

The problem with the consumption of psychoactive substances in the workplace has been the object of multiple studies, characterized by investigations on diverse populations of workers (deceased or hurt in a work related injury or subjects recruited with random criteria or for a toxicological control duty) and different methodologies of research (survey, chemicaltoxicological analyses on biological matrices, integrated approach) [18]. Despite the limitations of comparative interpretation, the results of the highlighted studies reveal that:


Given that such evidence does not patently allow for establishing the significance of the role of psychoactive substances, in the genesis of accidents at work, the need to implement systematic, international and national studies, including comparative analysis of anamnestic/ cathamnestic, clinical/autoptic and chemical-toxicological data, extended to multiple biologi‐ cal matrices (blood, urine and hair), exists.

There are guidelines elaborated by International Scientific Societies and statuary legislations that provide instructions for authorized laboratories to perform toxicological analyses in the work place frame. Such indications regard: the method of specimen collection and analysis; interpretation of results, also dependent on predetermined cut-off statutory values; internal and external monitoring of analytical quality; the manner of reporting.

Organization of toxicological controls on workers presumes therefore the application of uniform and standardised toxicological assessment, aimed at safeguarding the security of work places, also through acquisition of scientific epidemiological evidence.
