**5.1. Serodiscordant infection: Definition**

HIV natural resistance can best be described using serodiscordant HIV infection in sexual partners. Serodiscordant HIV infection recognises couples/sexual partners in which one may be either HIV seroconcordant-seropositive or seroconcordant-seronegative or the partners are having different serostatuses [46]. Serodiscordant HIV infection refers, therefore, to partners adequately exposed to HIV infection in which one is HIV positive (seropositive) and the other HIV negative (seronegative).
