Preface

Chapter 8 **Radiotherapy and Chemotherapy Treatments in Head and Neck**

Chapter 9 **A Close Look at Neutropenia among Cancer Patients — Risk**

Zeeshan Ramzan, Phat Le, Payal Kapur and Sergio Huerta

Chapter 11 **Recent Advances in the Management of Rectal Cancer 259**

Jeffrey Meyer, Jie J. Yao and Sergio Huerta

**and After RTP 165**

Bin Othman

**VI** Contents

Iruegas and Abel García-García

**Factor and Management 201**

Chapter 10 **Current Concepts in Pancreatic Cancer 225**

**Cancer Patients — Protocol for Management Before, During**

Paula Bonar Alvarez, Mario Perez-Sayans García, Maria Elena Padín

Bassam Abdul Rasool Hassan, Zuraidah Binti Mohd Yusoff and Saad

Notwithstanding the advances in the cancer research field, the related epidemiology data remain dramatic and clearly point to an urge to optimize and innovate the therapeutic ap‐ proaches to fight cancer. Indeed, the elucidation of important aspects of cancer biology and human tumorigenesis has progressively enabled oncologists to provide more accurate can‐ cer diagnosis, thus, guiding more efficiently the treatment of multiple cancer types and sub‐ types. Nonetheless, cancer treatment still challenges researchers and clinicians, as proven by the still impressive and increasing number of worldwide cancer-related deaths, caused ei‐ ther by late diagnosis of the disease, surgical limitations or radio/chemoresistance. Adding complexity to the inter-individual variables, cancer comprises multiple diseases harboring diverse genetic and epigenetic signatures, the types and subtypes of which respond differ‐ ently to treatment and are associated with distinct clinical outcomes. *Updates on Cancer Treat‐ ment* is an attempt to integrate into a book volume various aspects of cancer treatment, compiling comprehensive reviews written by an international team of experts in the field.

> **Leticia B. A. Rangel, Pharm.D., Ph.D. and Ian Victor Silva** Federal University of Espirito Santo Espirito Santo, Brazil
