**Acknowledgements**

The chapter was prepared within collaborative projects: Centre of Excellence for International Research CZ.1.07/2.3.00/20.0164 to JT, MR and ADM. We gratefully acknowledge the support by Project Centre of Excellence for Nanotoxicology GACR GAP503/12/G147. Štěpán Koudelka was supported by European Regional Development Fund – Project FNUSA–ICRC (No. CZ. 1.05/1.1.00/02.0123), European Social Fund and the State Budget of the Czech Republic – Project FNUSA - ICRC - Support for neurological R&D teams through new postdoc positions formation (No. CZ.1.07/2.3.00/30.0043). The author´s team was supported by the project FIT.

The support by Global Acorn is kindly acknowledged and appreciated.
