**6. Conclusions and future trends**

From the work presented in this chapter, it is clear that amine plasma based techniques are powerful versatile tools to modify a material surface in order to make it more biocompatible. However, despite the vast array of choices offered by plasma processing techniques, there remain a significant number of hurdles that must be overcome to allow this methodology to realize its full potential in the area of biocompatible materials. Challenges include issues associated with analytical characterization, material structure, plasma processing, and uniform composition and thickness following treatment. A better understanding of the cellbiomaterial interactions is of crucial importance providing us with essential clues about which strategies should be pursued. As our fundamental understanding of these complex phenom‐ ena further develops, better control over cell adhesion, proliferation and differentiation will be achievable. Up till now, plasma surface modification is mostly studied on two-dimensional substrates but it can be expected that the study of 3D porous scaffolds will become more important. It is believed that, in the future, a broader exploration of various plasma strategies, monomers and biomaterials will enable us to achieve homogeneous scaffolds with desired mechanical, chemical and biodegradation properties in an industrialized setting.
