**Meet the editor**

Dr. Tarek A Ahmed completed his undergraduate and master's degree from the Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt. He received his PhD from Texas A&M Health Science Center, Texas, USA. Over the years, Dr. Tarek gained vast experience and excellent teaching skills through his handling of all of the pharmaceutical practical and theoretical courses for under-

graduate and postgraduate students, especially those that deal with pharmacokinetics and biopharmaceutics. Besides his teaching skill, Dr. Tarek has a lot of international publications in different pharmaceutical scientific research journals such as *International Journal of Pharmaceutics*, *Journal of Microencapsulation*, *AAPS PharmSciTech*, *Drug Development and Industrial Pharmacy*, *Pharmaceutical Development and Technology*, *International Journal of Drug Delivery*, *International Journal of Nanomedicine*, *Life Science*, and others.

## Contents

**Preface XI**


Chapter 6 **Clinical Pharmacokinetic Applications of Recirculatory Models 137** José M. Lanao and Clara Isabel Colino

## Preface

The purpose of this book is to provide undergraduate and postgraduate students of pharma‐ cology with the basic as well as the newly applied concepts of pharmacokinetics. An overview of the concept of pharmacokinetics and biopharmaceutics in addition to the scientific terms used in pharmacokinetic equations along with some examples and basic problems in pharma‐ cokinetics are illustrated. This will help undergraduate students understand the concept of absorption, distribution, metabolism, and elimination from common routes in the body fol‐ lowing drug administration. The book also highlights clinical aspects in the pharmacokinetics of some antimalarial drugs and spread of drug resistance, recirculatory models.

Each chapter in this book is written at a level that is appropriate for students or those who are interested in this area of study and contains an introduction that clarifies the basic con‐ cepts described therein.

Finally, we acknowledge the effort and contribution of all the authors, coauthors, editorial members, and others who helped in bringing this book to light.

> **Tarek A Ahmed, Ph.D.** Associate Professor of Pharmaceutics Department of Pharmaceutics Faculty of Pharmacy, KAU
