**Meet the editor**

After completing his basic medical education (MBBS) at the National University of Singapore in 1987, Dr. Ong was accepted as a member of the Royal College of Physicians (MRCP) in the United Kingdom in 1993 and subsequently completed his specialist training in Respiratory Medicine at the Singapore General Hospital. In 1996 and 1997, Dr. Ong was a Fellow in the

Department of Pulmonary and Critical Care Medicine, Stanford University Medical Center, USA, and was also a visiting clinical and research Fellow in the Stanford Sleep Disorders Clinic and Research Center, USA. Dr. Ong has been a Fellow of the Royal College of Physicians (FRCP) in Edinburgh since 2002. He is also a Fellow of the American College of Chest Physicians (ACCP). Dr. Ong is the President of the Chronic Obstructive Pulmonary Disease Association (Singapore) and is recognized by the Global Initiative for Chronic Obstructive Lung Disease (GOLD) as the National Leader in Singapore. He presently is in private specialist practice at the Mount Elizabeth Medical Centre, Singapore.

Contents

**Preface VII**

Stoeger

Masaki Fujita

Chapter 1 **Lung Inflammation, Oxidative Stress and Air Pollution 1** Elisa Couto Gomes and Geraint Florida-James

Chapter 2 **Macrophage Polarization in Lung Biology and Diseases 29**

Chapter 3 **The Role of MMPs in the Progression of Chronic Lung**

Chapter 4 **Nature and Consequences of the Systemic Inflammatory Response Induced by Lung Inflammation 79** Kunihiko Hiraiwa and Stephan F. van Eeden

**Inflammatory Diseases 59**

Leema George, Swapna Upadhyay, Koustav Ganguly and Tobias
