**Meet the editor**

Dr. Yongzhi Xi graduated from BINZHOU Medical College and Academy of Military Medical Sciences, P.R. China, in 1982 and 1988 respectively, and trained at the Institute of Applied Radiobiology Immunology/TNO, The Netherlands, during 1991-1992. Since 1996 he has been Professor of Medicine and Hematology/Immunology, Chief of Immunology Laboratory, Beijing 307

Hospital Affiliated to Academy of Medical Sciences, Beijing. He has been engaged in studies on hematology/immunology, especially for HLA structure, function and clinical typing for HSC and organ transplantation. He has published over 180 articles in the scientific literature, covering various aspects of hematology/immunology research and has authored 6 books. Also, he has been the recipient of many science/technology awards and the member of many Science Societies/Associations.

Contents

**Preface VII**

Bade-Doeding

**MHC Cluster 61**

**Torrent PGM 141**

Masahito Katahira

**Section 1 Basic Aspects of Human Leukocyte Antigens 1**

Chapter 1 **Statistic and Analytical Strategies for HLA Data 3**

Chapter 2 **HLA Class I Polymorphism and Tapasin Dependency 41**

Chapter 3 **HLA-E, HLA-F and HLA-G — The Non-Classical Side of the**

Santos, Manuela Lima and Jácome Bruges-Armas

Chapter 5 **In Phase HLA Genotyping by Next Generation Sequencing — A Comparison Between Two Massively Parallel Sequencing**

**Bench-Top Systems, the Roche GS Junior and Ion**

**Section 2 HLA-Associated Important Autoimmune Diseases 183**

Chapter 6 **The Relationship Between Human Leukocyte Antigen Class II**

Jerzy K. Kulski, Shingo Suzuki, Yuki Ozaki, Shigeki Mitsunaga,

**Genes and Type 1 Diabetes, Autoimmune Thyroid Diseases, and Autoimmune Polyendocrine Syndrome Type 3 185**

Chapter 4 **Human Leucocyte Antigen Matching Strategy 111**

Hidetoshi Inoko and Takashi Shiina

Soumya Badrinath, Trevor Huyton, Rainer Blasczyk and Christina

Iris Foroni, Ana Rita Couto, Bruno Filipe Bettencourt, Margarida

Fang Yuan and Yongzhi Xi

Yuying Sun and Yongzhi Xi
