**8. Conclusion**

Epileptic seizures are common in patients with brain tumors. The mechanisms laying beneath the pathogenesis of tumor related epilepsy remain substantially unclear. Epileptogenicity might be generated by the tumor itself because of the intrinsic characteristics or the impaired balance between excitation and inhibition arising due to insufficient homeostasis in the peritumoral zone might be the reason where also metabolic, immunological and inflammatory alterations might be contributing. Thereby, clarifying both tumoral and peritumoral patho‐ physiology would lead in selecting the most convenient medical treatment. Recently, oxidative stress is suggested to be having a crucial role in brain tumor associated epileptic seizures as a means of mitochondrial dysfunction. Yet it should be enlightened with future studies weather treatment with antioxidant compounds would be beneficial on attenuating epileptic seizures. On the other hand, as there are no detectable inflammatory biomarkers with proven signifi‐ cance for epilepsy yet, the challenge should also be defining specific biomarkers which would be helpful in the diagnosis of antiinflammatory or immunomodulatory therapy effects. Apparently, bringing novel concepts out in the treatment strategies for brain tumor related epilepsy should be the main target in the future.
