**Meet the editor**

Dr. Morgan is a clinical pharmacologist and oncologist whose research interests are focused on developing new and novel agents that penetrate the CNS and are effective against both CNS primary and metastatic cancers. Dr. Morgan is currently CEO of DEKK-TEC, Inc. in New Orleans, Louisiana.

Contents

**Preface VII**

**Section 1 CNS Cancer – Past, Present and Future 1**

Siddharth K. Joshi and Richard Zuniga

**We Are; Where We Are Going 31**

**Section 2 New Diagnostic Approaches – CNS Tumors 61**

Piercarlo Fania and Angelina Cistaro

Yasushi Shibata

**Future Directions 3**

Chapter 1 **High Grade Glioma — Standard Approach, Obstacles and**

Chapter 2 **Paediatric Brainstem Cancers — Where We Have Been; Where**

Adrianna Ranger, Navjot Chaudhary and Jonathan Lau

Chapter 3 **Spatial Relationships of MR Imaging and Positron Emission**

**Generation in Glioblastoma Multiforme 63**

Chapter 4 **New Application of 123I-Iodoamphetamine SPECT for the**

**Section 3 Neurobiochemical – Considerations for the Future 103**

Chapter 5 **Biochemical and Surgical Aspects of Epilepsy Related to Brain**

**Tomography with Phenotype, Genotype and Tumor Stem Cell**

**Diagnosis of Primary Central Nervous System Lymphoma 95**

**Tumors — Appraising Redox Biology and Treatments 105** Pinar Atukeren, Taner Tanriverdi and M. Ramazan Yigitoglu

Davide Schiffer, Consuelo Valentini, Antonio Melcarne, Marta Mellai, Elena Prodi, Giovanna Carrara, Tetyana Denysenko, Carola Junemann, Cristina Casalone, Cristiano Corona, Valentina Caldera, Laura Annovazzi, Angela Piazzi, Paola Cassoni, Rebecca Senetta,
