**Meet the editor**

Dr. Felix Friedberg received the B.S. in Chemistry from the University of Denver (1944) and the Ph.D. in Biochemistry from the University of California, Berkeley (1947). He joined the faculty of the Biochemistry Department at Howard University Medical School (Washington, DC) as an instructor (1948) and there he advanced through the ranks to a full professorship. He has published more than one hundred papers in prominent scientific journals usually with co-workers on such topics as: Incorporation of C14 labeled glycine into the protein of tissue homogenates (Fed Proc 1948). Studies in protein metabolism of the amphibian embryo (J Exptl Zool 1949). On carbon dioxide fixation in vivo (J Biol Chem 1952). The carboxylation of propionic acid by liver mitochondria (J Biol Chem 1956). Gamma irradiation of polypeptides: Transformation of amino acids (Science 1963) Ion binding by ATP-creatine phosphotransferase (J Biol Chem 1966). Cloning and characterization of the beta-amylase gene from Bacillus polymyxa (J Bact 1986). Calculation and verification of the ages of retroprocessed pseudogenes (Mol Phylogenet Evol 2000). Calmodulin genes in Zebrafish (Mol Biol Rep 2005). Single and multiple CH domain containing multidomain proteins in Dictostelium discoideum (Mol Biol Rep 2010). Professor Friedberg also authored two small books: Thoughts About Life (Philosophical Library, New York, 1954) and Caveat Homo Sapiens: The Furtive Mind (University Press of America, Inc 2000).

Contents

**Preface IX** 

**Part 1 General Aspects 1** 

Jinya Otsuka

Chapter 1 **A Theoretical Scheme of the** 

Chapter 2 **Duplicated Gene Evolution Following** 

Chapter 3 **Detection and Analysis of Functional** 

Klas Hatje and Martin Kollmar

Chapter 4 **Predicting Tandemly Arrayed** 

Chapter 5 **The LRR and TM Containing** 

Felix Friedberg

Chapter 6 **Partial Gene Duplication** 

Chapter 7 **Immunoglobulin Polygeny:** 

**Large-Scale Evolution by Generating New Genes from Gene Duplication 3** 

**Specialization in Duplicated Genes 37**  Owen Z. Woody and Brendan J. McConkey

**Gene Duplicates with WebScipio 59** 

**Multi-Domain Proteins in Arabidopsis 77** 

**and the Formation of Novel Genes 95** 

Macarena Toll-Riera, Steve Laurie, Núria Radó-Trilla and M.Mar Albà

**An Evolutionary Perspective 113**  J. E. Butler, Xiu-Zhu Sun and Nancy Wertz

**Part 2 A Look at Some Gene Families 111** 

**Whole-Genome Duplication in Teleost Fish 27**  Baocheng Guo, Andreas Wagner and Shunping He
