**1. Introduction**

[21] Blanes Orti P, Vázquez R, Minguell P, García V, Manuel-Rimbau Munoz E, Lozarno Vilardell P. Percutaneous revascularization of specific angiosome in critical limb is‐

[22] Varela C, Acin F, de Haro J, Bleda S, Esparza L, March JR. The role of foot collateral vessels on ulcer healing and limb salvage after successful endovascular and surgical distal procedures according to the angiosome model. Vasc Endovasc Surg

[23] Taylor G.I, Caddy CM, Waterson PA, Crock JG. The venous territories (venosomes) of the human body. Experimental study and clinical implications. Plast Reconstr

[24] Alexandriescu V, Ngongang C, Vincent G, Ledent G, Hubermont G. Deep calf veins arterialization for inferior limb preservation in diabetic patients with extended ische‐ mic wounds, unfit for direct arterial reconstruction; preliminary results according to an angiosome model of perfusion. Cardiovascular revascularization Medicine

chaemia. Angiologia 2011;63:11-17

2010;44:654-660

436 Artery Bypass

Surg 1990;86:185-

2011;12:10-19

In-hospital and long-term outcomes after Coronary artery Bypass grafting (CABG) are im‐ pacted by various factors including age, gender and various co-morbidities including chron‐ ic obstructive pulmonary disease, hypertension, diabetes Mellitus, dyslipidemia, chronic kidney disease (CKD), Peripheral arterial disease (PAD) and even connective tissue disor‐ ders such as systemic lupus erythematosus, and rheumatoid arthritis.

Both CKD and PAD have been considered a major risk factor for morbidity and mortality post-CABG [1]. Therefore, both are always considered as a variable when calculating risk for perioperative mortality in patients undergoing CABG in the popular EUROSCORE and society of Society of Thoracic Surgeons National Cardiac Surgery Database scoring system [1,2].

We will discuss the degree of importance of these co-morbidities along with the epidemiolo‐ gy, underlying proposed pathogenetic mechanisms, significant associated co-factors, and al‐ so highlight the pertinent existing data on these parameters.
