Contents



Preface

postherpetic neuralgia.

of inspiration.

Understanding the rapid changes in the evaluation and management of peripheral neuropa‐ thies, as well as the complexity of their mechanism, is a mandatory requirement for the practitioner to optimize patient's care. The objective of this book is to update health care professionals on recent advances in the pathogenesis, diagnosis and treatment of peripheral neuropathy. This work was written by a group of clinicians and scientists with large exper‐ tise in the field. In the first chapter of section one, Dr Emily A Ramirez and collaborators reviewed the pathogenesis of neuropathic pain and identified the anatomical pathways and the molecular mechanism of neuropathic pain. They reviewed the interaction between the central and peripheral nervous system in chronic pain as well as its clinical assessment and treatment. In the second chapter of section one, Dr Chengyuan Li and collaborators re‐ viewed the pharmacological management of diabetic neuropathy. This was based on trans‐ lational research from animal models of diabetic peripheral neuropathy. In the third chapter of section one, Dr Sabatino Maione and collaborators reviewed the complex mechanisms of painful neuropathy involving the central and peripheral nervous system. Based on these mechanisms, they evaluated the use of cannabinoids and stem cells for the treatment of pe‐ ripheral neuropathy. Dr Mendoza and Dr Salgado reviewed the diagnosis and management of compressive neuropathies in the first chapter of section two. In the second chapter of this section, Dr Jáuregui-Renaud provided a comprehensive review on the role of Postural bal‐ ance in the evaluation of peripheral neuropathy. In the last chapter of section two, Dr Kan‐ bayashi and Dr Hosokawa reviewed the most recent advances in the pharmacotherapy of

I dedicate this work to the memory of my father, for his enduring love and guidance throughout my career, he continued to serve as a source of inspiration. I extend my grati‐ tude to my mother for her love and affection. I am continuously indebted to my wife Sonia for her love, unconditional support and encouragement, without her help and sacrifice, this work would not have been possible. I am also grateful to my son Sami and my beautiful daughters Leila and Nora for their love and energy which continue to be a valuable source

**Dr Nizar Souayah**

Neuromuscular Medicine Program Director Director of Peripheral Neuropathy Center Department of Neurology and Neuroscience

University of Medicine & Dentistry of New Jersey, USA
