**9. Hyperbaric oxygen therapy**

Theoreticallys, the restitution of blood supply to the injured area is fundamental for the regeneration process, in particular for the myotubes which depend soley on aerobic metabo‐ lism as the source of energy required for their regeneration. This is the basis for the application of Hyperbaric Oxygen Therapy in muscle lesions. Clinical trials are lacking, however a recent experimental study showed positive effects of this treatment on muscle injury. Further research should assess the clinical outcome of Hyperbaric Oxygen Therapy before it may be suggested for this kind of pathology [33].
