**16. Conclusion remarks**

Biocompatible is a vital important aspect for an implantable biomaterial. Among the numer‐ ous types of host responses to a broad spectrum of biomaterials, those with no adverse or negative effects, such as, fibrous encapsulation, osteolysis, hyperplasia, and inflammation are among the most expectant ones. As advances are made in biomaterial science and tech‐ nology, new implants/medical devices will be continually explored, alternatives to conven‐ tional implants will become more and more effective, and hence more and more attractive. In an effort to provide the best clinical outcomes for the patients, we need to develop the best candidates with minimum invasive surgery times and unnecessary health risks. In the future, design and manufacture immuno or low-immuno implantable biomaterials accord‐ ing to or mimicking the patients' own ingredients, such as blood components, ECMs, tissues and organs, will be possible. For an implantable biomaterial biocompatibility should be al‐ ways put into the primary importance position no matter it is used as a temporary scaffold, a permanent template, or a drug delivery vihicle.
