**Acknowledgements**

Our work is supported by grants from the Institut National de la Santé et de la Recherche Médicale (Inserm), Association Française contre les Myopathies (AFM), Association Française pour la Recherche sur la SLA (ARS), Direction de l'Hospitalisation et de l'Organisation des soins (DHOS) and the Thierry Latran foundation. M.B is a recipient of a long-term EMBO Marie Curie Fellowship. We apologize to authors whose work could not have been cited due to space limitations.

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