**Author details**

scattering is a phenomenon that influences the image formation in OCT: photons that are singly scattered add to the OCT signal, whereas photons that are scattered multiple times contribute to the background noise [31]. The large amount of water within the eye limits the light wavelengths that can be used [32]. The absorbtion spectrum of water has two regions where the light absorbtion is low: at approximately 950 nm and between 1,000-1,100 nm [30]. The devices with wavelenghts in the range of 1,000-1,100 nm can be used for the enhanced sub-RPE imaging, with ultrahigh-speed image aquisition and axial resolution in the range of 8 μm [10]. This is useful in the managements of sub-RPE space

156 Age-Related Macular Degeneration - Etiology, Diagnosis and Management - A Glance at the Future

Adaptive optics correct ocular aberrations during image aquisition, making possible the ob‐

The principle of Enhanced depth imaging OCT (EDI-OCT) consists in placing the objec‐ tive lens of the Spectralis SD-OCT device (Heidelberg Engineering) closer to the eye, with the obtaining of an inverted image, which allows the deeper structures to be placed closer to the zero delay with the subsequent better visualization of the choroid. This principle is combined with the high speed scanning, eye-tracking system, image-averag‐ ing technology, reduced noise and greater coverage of the macula. All these improve‐ ments lead to the possibility to create high resolution, repeatable and reliable images of

At the present moment, OCT offers the most valuable data on the retinal structure. AMD is the retinal disease that benefited the most from the development of OCT techniques, espe‐ cially the wet form of this disease. SD-OCT has superior depth resolution as compared to TD-OCT: currently, the axial resolution varies from 3 – 7 μm, depending on the SD-OCT model. OCT is more reliable than biomicroscopy in assessing the macular thickness and small neurosensory and RPE detachments. OCT is more reliable than FA in identifying the intraretinal and subretinal fluid, as on FA the fluid in the inner retina can mask the fluid in the outer retina. OCT is less precise in evaluating the geographic extent of fluid within the macula, as compared to FA. Due to the cross-sectional imaging, OCT allows the localization of a CNV in relationship with the RPE and the neurosensory retina. OCT is superior to FA in identifying CNV membranes that are obscured by pooling of dye or by tiny retinal haemor‐ rhages. Cystoid macular edema is strongly associated with the classic CNV. OCT is very useful in AMD monitoring and decision-making after treatment: if fluid persists, re-treat‐

diseases, particularly in AMD.

**9.4. Enhanced Depth Imaging OCT**

taining of image resolution at the cellular level.

**9.3. Adaptive optics**

the choroid [33].

**10. Conclusion**

ment is indicated.

Simona-Delia Ţălu

Address all correspondence to: simonatalu@yahoo.com

Department of Surgical Sciences and Medical Imaging, Ophthalmology, "Iuliu Haţieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania
