Contents

#### **Preface XI**


#### X Contents



Preface

Atrial fibrillation is a rapidly evolving epidemic associated with increased cardiovascular morbidity and mortality, and its prevalence has increased during the past few decades. In the past few years, the recent understanding of the diverse mechanisms of this arrhythmia has led to the improvement of our therapeutic strategies. However, many clinicians have

This book contains a spectrum of different topics from bench to bedside in atrial fibrillation. We try to introduce the most recent advancement of mechanisms and treatment of AF including genetics, calcium signaling, thrombogenesis, signal analysis, upstream therapies focus on re‐ nin-angiotensin-aldosterone system inhibitors, antioxidants and n-3 polyunsaturated fatty acids, and anticoagulation issues. I strongly believe that scientists, cardiologists and electro‐ physiologists will find this book very informative and useful. The references cited in each

I am grateful to the all the authors who contributed to this book with their valuable experi‐ ence. I also appreciate the great help from InTech editorial office, Ms. Mirna Cvijic and Mr. Dejan Grgur, who guided me through the publication process step by step. I would also like to thank for the important contributions from the co-editors of this book – Prof. Guangping Li, my mentor, and Dr. Panagiotis Korantzopoulos, my best friend who guided me to ex‐ plore the wonderful world of arrhythmia. Finally, special thanks to my family – wife, Lijian,

**Tong Liu, MD, PhD**

People's Republic of China

Department of Cardiology, Tianjin Institute of Cardiology Second Hospital of Tianjin Medical University, Tianjin

still felt the frustration in management of this commonly encountered arrhythmia.

chapter will definitely act as additional source of information for readers.

and son, Yujie, who provided continuous inspiration and support to my work.

