**Acknowledgements**

Laboratory of Bioengineering and Tissue Regeneration-University of Málaga (LABRET-UMA) is supported by grants from the Spanish (PI10/02529, and Red de Terapia Celular, RD06/00100014), and the Andalusian Governments (PI-0729-2010, and PAID BIO217). CIBER-BBN is an initiative funded by the VI National R&D&I Plan 2008-2011, *Iniciativa Ingenio 2010, Consolider Program, CIBER Actions* and financed by the Instituto de Salud Carlos III (Ministry of Economy and Competitiveness) with assistance from the *European Regional Development Fund.*

The authors have written this chapter in collaboration with Dr. Avedillo, Scientific Director of the company Innovaxis Biopharmaceuticals Ltd., with which we have established an agree‐ ment regarding patent number WO 2012001124 A1, referenced below.
