**Meet the editor**

Dr. Monica Fedele is lead researcher at the Institute of Experimental Endocrinology and Oncology of the National Research Council in Italy. She graduated in Biological Sciences at the University of Naples, receiving her PhD in Cellular and Molecular Biology and Pathology, and residency in Clinical Pathology, at the Medical School of the same University. Dr. Fedele trained in mo-

lecular oncology and was a postdoctoral investigator in USA, focusing on the development of transgenic and knockout mice for the HMGA genes. Her main scientific achievements are the isolation and characterization of the cancer-related gene PATZ, the demonstration of the oncogenic activity of the chromatin proteins HMGA1 and HMGA2, and the discovery of their critical role in the development of pituitary adenomas.

Contents

**Preface VII**

Annamaria Colao

**Salt Iodization 101**

and Camelia Gliga

Benjamin U. Nwosu

and Carmen Sanz

Carnovale

Chapter 1 **Hereditary Neuroendocrine Tumor Syndromes 1**

Chapter 3 **Aging and Subclinical Thyroid Dysfunction 85** Corrêa V. M. da Costa and D. Rosenthal

Chapter 5 **Diabetes and Its Hepatic Complication 129**

**Children and Adolescents 145**

Chapter 4 **Detection of Iodine Deficiency Disorders (Goiter and**

Chapter 6 **Double Diabetes: The Search for a Treatment Paradigm in**

Chapter 7 **Glucagon-Like Peptide-1 and Its Implications in Obesity 165**

Antongiulio Faggiano, Valeria Ramundo, Luisa Circelli and

Marie-Lise Jaffrain-Rea, Sandra Rotondi and Edoardo Alesse

**Hypothyroidism) in School-Children Living in Endemic**

**Mountainous Regions, After the Implementation of Universal**

Imre Zoltán Kun, Zsuzsanna Szántó, József Balázs, Anisie Năsălean

Paola I. Ingaramo, Daniel E. Francés, María T. Ronco and Cristina E.

Veronica Hurtado, Isabel Roncero, Enrique Blazquez, Elvira Alvarez

Chapter 2 **New Insights in the Pathogenesis of Pituitary Tumours 27**
