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Lisa Passantino1\*, Max Costa1 and Mary Matsui2


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**Chapter 8**

**Photodynamic Therapy for Non-Melanoma Skin Cancer**

Skin cancer shows the highest incidence worldwide, among all cancer types, and is mainly

Clinical evaluation through dermatoscopy is a widely performed practice, and it is a nonin‐ vasive technique that uses magnification to allow better visualization of the structures immediately below the skin surface. This examination provides morphological criteria for

Histopathology is considered the gold standard for diagnosis of skin cancer and other dermal disorders. These two exams together, as well as the location and extent of the injury will

Treatments such as surgical excision, cryotherapy, topical application of imiquimod cream and 5-fluorouracil cream, and radiotherapy are commonly chosen based on the depth and exten‐ sion of the lesions. Limitations and side-effects of the conventional therapies motivate the development of other techniques. Photodynamic therapy (PDT) is presented as an alternative

PDT has proven to be effective with an excellent cosmetic outcome in the treatment of superficial BCC (sBCC), and recently published guidelines state that PDT can be an effective and reliable treatment option for the treatment of thin nodular BCC (nBCC), and actinic keratosis (AK) [1]. It is a technically simple noninvasive procedure that offers patients at least equal efficacy and a high level of satisfaction and other cosmetic outcome when compared with

and reproduction in any medium, provided the original work is properly cited.

© 2013 Andrade et al.; licensee InTech. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

© 2013 The Author(s). Licensee InTech. This chapter is distributed under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution,

Cintia Teles de Andrade, Natalia Mayumi Inada,

Vanderlei Salvador Bagnato and Cristina Kurachi

Additional information is available at the end of the chapter

classified in melanoma and non-melanoma subtypes.

distinguishing various lesions types.

determine the choice of treatment.

treatment for basal cell carcinoma (BCC).

cryotherapy and topical treatments [2].

Dora Patricia Ramirez,

http://dx.doi.org/10.5772/55242

**1. Introduction**

