**8. Special considerations in ANCA Associated Small vessels Vasculitis AASV**

Therapeutic targets that are currently being considered in ANCA associated vasculitis include: (a) Inhibition of adhesion and activation of neutrophils aiming to dampen vascular injury. (b) Boosting vascular repair via endothelial progenitor cells (EPCs) which are regarded as an important factor of vascular repair. EPC mobilization and function might be enhanced by additional treatment with erythropoietin (EPO) or statins. (c) The use of antibiotics (cotrimox‐ azole) might prevent disease flares triggered by bacteria.
