**10. Treatment**

At present, only herpes simplex encephalitis, one of the more prevalent infective encephali‐ tis, has a specific treatment validated by scientific research. It is treated with aciclovir [101]. Effective treatment is lacking for other viruses and mainly symptomatic in nature.

Currently, intravenous immunoglobulin (IVIG) is administered to patients with severe HFMD [5]. Enteroviruses are cleared from the host by antibody-mediated mechanisms (22), and IVIG is an effective treatment option. Various routes of administration have been docu‐ mented including intravenous, intrathecal and intraventricular with different degrees of success [102-104].
