Contents

#### **Preface XI**

#### **Section 1 Encephalitis Clinical Diagnostics and Treatment 1**


Chapter 7 **Genetic and Biological Properties of Original TBEV Strains Group Circulating in Eastern Siberia 95**

I.V. Kozlova, M.M. Verkhozina, T.V. Demina, Yu.P. Dzhioev, S.E. Tkachev, L.S. Karan, E.K. Doroshchenko, O.V. Lisak, O.V. Suntsova, A.I. Paramonov, O.O. Fedulina, A.O. Revizor and V.I. Zlobin

Chapter 8 **The Pathomorphology of Far Eastern Tick-Borne Encephalitis 113**

Larisa M. Somova, Galina N. Leonova, Natalia G. Plekhova, Yurii V. Kaminsky and Anna Y. Fisenko

Preface

additional book.

instructions for encephalitis diagnostics.

has high pathogenic potential.

hypotension that could be erroneously taken for encephalitis.

Encephalitises are a group of inflammatory human and animal diseases of brain caused essentially by different pathogens. In spite of evident success in approaches for prevention, diagnostics and treatment during the last decades, the encephalitises of different etiology

Recently, three-volume book was published by InTech, including the first "Flavivirus Encephalitis" (edited by Daniel Růžek), the second "Non-Flavivirus Encephalitis" (edited by Sergey Tkachev) and the third "Pathogenesis of Encephalitis" (edited by Daisuke Hayasaka) parts, which can be found on InTech site (http://www.intechopen.com). But a lot of different aspects and information were not included in these volumes so we decided to publish the

The first part of this book is devoted to encephalitis clinical diagnostics and treatment. Proper diagnosis definition is an important step in encephalitis treatment so the 1st chapter considers the questions of clinical management of the patient and includes step-by-step

In some cases the abnormalities in encephalitis clinical course or symptoms similar to encephalitis can be observed so the physicians should pay special attention to such patients. The 2nd and 3rd chapter describe the cerebrospinal fluid abnormalities that could be seen in some cases during the viral encephalitis and the cases of spontaneous intracranial

One of the important questions of any pathogen study is the epidemiology and monitoring and prediction of the epidemiological situation. Chapters 4 and 5 give the example of such

The members of different virus species are known to be the causative agents of encephalitis, so the second part of the book is devoted to viral pathogens, their epidemiology, pathology and diagnostics. Probably, the arboviruses (and especially members of the genus Flavivirus) are known to be one of the most known and frequent causative agents of encephalitis, so the following chapters are about arboviruses-induced encephalitises. The short review on causative agents of arboviral encephalitis is presented in Chapter 6. Chapters 7-12 are devoted to flaviviruses, their epidemiology, pathology and vaccine design. The attention should be paid to chapter seven which presents new tick-borne encephalitis virus group that was demonstrated to cause focal forms of tick-borne encephalitis with lethal outcome and

Other virus species are also known to be the causative agents of encephalitis, so the last chapters are devoted to non-arbovirus pathogens. Chapter 13 describes the fatal case of

monitoring of the encephalitis cases caused by viral pathogens in Japan and Nepal.

still constitute a menace for thousands of people all around the world.

Chapter 9 **Active Natural Foci of Tick-Borne Neuroinfection in the North-West Region of Ukraine 145**

I. Lozynski, H. Biletska, O. Semenyshyn, V. Fedoruk, O. Drul, I. Ben, A. Shulgan and R. Morochkovski


Tomoyuki Honda, Misako Yoneda, Hiroki Sato and Chieko Kai

Chapter 15 **Viral Encephalitis with Focus on Human Enteroviruses 263** Po-Ying Chia and Justin Jang Hann Chu
