**Acknowledgements**

core-shell nanofibers were prepared by the seed-mediated growth Au shell on electrospun SiO2 nanofibers [240]. Then horseradish peroxidase (HRP) was immobilized on the SiO2@Au nanofibers modified electrode via physical adsorption to construct an amperometric H2O2 biosensor. This biosensor exhibited high biological affinity to H2O2 and the HRP enzyme on

**Figure 14.** (A) Typical SEM images of Hb microbelts at low (scale bar=10 μm) and high (inset, scale bar=1 μm) magnifi‐ cation; (B) CVs of the bare GC electrode (a) and Hb microbelts modified GC electrode (b) in 0.1 M pH 7.0 phosphate

In past few years, numerous studies have demonstrated that elctrospinning is a simple and versatile method for fabricating nanofibers of organic or inorganic materials. Various func‐ tional components, such as nanoparticles, CNTs, proteins, DNA and so on, have been incor‐ porated into the electrospun nanofibers. These composite nanofibers exhibited excellent properties and extended the applications of electrospun nanomaterials. With the profound understanding the electrospinning process and the development of setup for electrospinning,

the gold shell kept its activity with a low-diffusion barrier.

62 Advances in Nanofibers

buffer solution. Scan rate, 100 mV s-1 [237].

**5. Conclusions and remarks**

This work was financially supported by the National Nature Science Foundation of China (NO. 21155002, 21105098, 21222505).
