**7. Comment**

In the light of the wide use of immunosuppressive therapy, in particular in the era of biolog‐ ical therapies in rheumatic diseases, close attention should be paid to the possible reactiva‐ tion of latent infections. Most commonly tuberculous infection should be considered, but viruses like Cytomegalovirus (CMV) may also be present in patients in their persistent form. In similar circumstances - in AIDS patients and patients after organ transplantations (e.g. bone marrow transpaltation) - CMV retinitis has been reported. Currently there are reports of CMV retinitis in the course of treatment RA with infliximab (anti TNF) [94].

Finally, it should be noted that biological drugs have proved effective in the treatment of oc‐ ular manifestations of many rheumatic diseases and the exclusion of potential infection is particularly important for the choice of treatment and safety of therapy.
