**1. Introduction**

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analysis of basophil activation. Inflamm Res. 1996;45:S35-S36.

mine release and flow cytometric

60 Common Eye Infections

Bacterial and fungal corneal infections are characterized by the presence of a replicating mi‐ croorganism as the cause of inflammation, and loss of corneal epithelial cells and ulcers, as the last expression of inflammatory phenomenon [1]. Clinically, it is difficult to establish a diagnosis of bacterial keratitis specifically the causal agent. For this reason, the use of labora‐ tory techniques is extremely important to establish a diagnosis. Clinical data created a sus‐ pected diagnosis, but results from the laboratory, particularly crops, studies represent the fundamental basis for a definitive diagnosis. Microbiological culture is the only way to de‐ termine the sensitivity to antibiotics and guide therapy to achieve optimal management of these conditions [2].

The active replication agents of the infectious ulcers can be viruses, bacteria, fungus *Acantha‐ moeba* or *Microsporidium*. An early detection of causative of microorganism helps to a better and specific medical treatment in order to reach a better prognosis, visual acuity and even preservation of the ocular integrity.
