**6. Conclusion**

Type 1 diabetes is a complex multifactorial disease. The involvement of enteroviruses as a major non-genetic etiological factor is a topic of reflexion for several research teams world‐ wide. Studies from these teams have shown that enteroviral infections, especially coxsackie‐ virus B infections, are closely linked with T1D. Findings from experimental in vitro and in vivo studies have lightened the potent role that can play enteroviruses in inducing and/or worsening the disease. However, in certain particular conditions, enteroviruses can induce a protective effect in mouse model. Therefore, further studies are needed to understand the mechanisms behind this complex relationship between enteroviruses and T1D.
