**2. The dispute and problems about prognosis**

**7.** Coefficient of outflow facility (C value) descends in episodes and recovery as IOP in intermission; various stimulation tests for glaucoma are negative in intermission.

**8.** The forms of onset of PSS could be divided into three kinds: KP, high IOP and intermediate

**Figure 1.** Anterior segment of a case with PSS in episodes. Arrows indicate the typical hoar and suet-shaped KP.

The patient complained of her blurred vision two months ago, examination in other hospital showed: conjunctiva of her left eye wasn't congestive and the cornea was edematous mildly, IOP: 34/ 18(R/L) mmHg; there were some round lipid-like KP in the left cornea, aqueous flare (-). She came to our hospital on June 7, 2012, ophthalmologic examination: vision was 0.5/ 1.5(R/ L), best corrected vision of left eye was 1.2(-1.25DS), IOP: 18/ 13 (R/L) mmHg. Her right eye was normal, conjunctiva of her left eye wasn't congestive and there were five rounds lipid-like KP in the left cornea, binocular C/D was 0.4. Her KP faded away after the treatment of chloromethyl and pranopulin (three times a day) for three weeks. Examination of FFA, ICGA and Virus screening were normal on July 10.The measurement of her 24 hours IOP performed two weeks after she ceased the drugs was 20-14mmHg(R), 15-12 mmHg (L). The result of her visual field and the OCT for glaucoma was normal. She was diagnosed as PSS in left eye and

**1.** Anti-inflammation: Corticosteroid drugs is needed in most cases, but it should not be used

It is a better select in some cases to apply non-steroidal anti-inflammatory drugs (NSAIDs)

Reducing IOP: Eye drops of epinephrine, timolol,or clonidine was needed singly or jointly for common patient, carbonic anhydrase inhibitor orally when the IOP is higher than 30mmHg

too long a time, so as not to cause the corticosteroid glaucoma.

such as eye drops of pranoprofen, indomethacin and flufenamic acid.

and mannitol of intravenous drip when the IOP is higher than 40mmHg.

type, according to relationship between KP and IOP.

**Typical case**

382 Glaucoma - Basic and Clinical Aspects

suggested to be observed and treated timely.

**1.5. Treatment of typical cases in episodes**

It was considered in the early years that PSS have a favorable prognosis without glau‐ comatous damage of optic disk and visual field, however, a number of authors have con‐ firmed that part of the PSS cases suffered from glaucomatous damage similar to that in primary glaucoma patients in recent years. A lot of questions remained vague such as monocular or binocular, age of onset, the detailed features of its IOP and KP, the inci‐ dence and degree and relating factors of glaucomatous damage, especially the clinical approaches via which the damage occurred and disease complicated with PSS. These brought about to two undesirable consequences: first, PSS patients were misdiagnosed as primary glaucoma and received incorrect treatment even led to serious adverse conse‐ quences due to the lack of knowledge on the clinical characteristics of PSS.On the other hand, most cases of PSS combined with primary glaucoma patients especially these with primary angle-closed glaucoma were failed to be diagnosed correctly without delay, thus the best opportunity of treatment lost ; severe damage resulted in.

In order to solve the problems mentioned above, we have made a long-term systematic clinical study about PSS for more than 20 years persistently.
