**6.5. Splenectomy**

The role of splenectomy in treating ABMR is not yet known. Case reports have demonstrated that it may be useful as a rescue treatment in severe ABMR.[53] Majority of its use has been in preventing hyperacute rejection in ABOI transplants [54, 55]. There remains concern over the increased infection risk in splenectomised patients, particularly due to encapsulated organ‐ isms, and vaccination against Meningococcus and Pneumococcus is warranted where possible prior to splenectomy to mitigate this risk.
