**Acknowledgements**

We would like to thank Sarah Odrion for excellent editorial assistance and the Centre d'Investigation Clinique intégré en Biothérapies du CHU de Besançon (CBT-506) for its support. Our work in the fields was supported by grants from the Agence Nationale de la Recherche (Labex LipSTIC, ANR-11-LABX-0021 and ECellFrance consortium, ANR-11- INBS-0005), the Programme Hospitalier de Recherche Clinique 2011 (to D.D), the Fondation de France (Appel d'offre "Maladies cardiovasculaires" 2007, #2007 001859, to P.S.), the DHOS/ INSERM/INCa (Appel d'offre Recherche Translationnelle 2008, to D.D. and P.S.), and the APICHU 2010 (SIGAL project to J.B.).
