**12. Soy protein**

Soy protein mitigates lipotoxicity in the liver and pancreas in various rodent models of obe‐ sity. Dietary soy protein can suppress cardiac cholesterol and triglyceride concentrations and reduce cardiacceramide concentration by downregulating the expression of serine pal‐ mitoyl transferase, a key enzyme in sphingolipid biosynthesis in the heart of obese rodents, and by reducing lipid accumulation. Thus, soy protein consumption may be a useful dietary therapeutic strategy for l prevention of lipotoxic cardiomyopathy [15].
