**Author details**

Hilmiye Deniz ErtuğruL<sup>1</sup> and Zihni Onur Uygun2

1 Ondokuz Mayıs University, Turkey

2 Çanakkale Onsekiz Mart University, Turkey

## **References**

**Analyte Bioreceptors LOD Linear Range Reference**

1x101.2ELD50/ml 1x101.2ELD50/ml-

CramoLLLectin 25 µg/ml 25-200 µg/ml [31]

0.01µg mL-1 and 0.02nM, respectively

1x105.2ELD50/ml

0.2-40 nM Adenosine [25]

1.0×10−12M 7.0×10−12–2.0×10−7M [26]

[36]

17β-estradiol Estrogen Receptor-α 1.0x10-13M 1.0x10-1.0x10-11M [8]

Atrazine Anti-atrazine Antibody 10 fg/ml 10 fg/ml-1ng/ml [11]

Concavalin A Glucose 1.0 pM 3.3pM-9.3nM [29] Der f2 Murine Monoclonal Antibody 2.0 µg/ml 2-300 µg/ml [12] Glucose 3T3-L1 Fibroblast Cells 0-14 mM [32]

PS exerted cells Annexin V 5 Fu [34] Thrombin Thrombin Aptamer 0.013 nM 0.1-30 nM [35] VEGF VEGFR-1 100 fg/ml 100-600 fg/ml [4]

Consequently, biosensor systems have been developing, the most important factors are selec‐ tivity and low cost. These specialties are very important of Point-Of-Care usage. Electrochem‐ ical impedance spectroscopy is very effective technique for label-free molecule detection. It can provide sensitivity, low cost and selective biosensor systems. As you can read from above, by using specific molecules such as DNA, Aptamer, Receptor, Antibody, Specific Proteins etc. it is

possible to construct selective and sensitive impedimetric biosensor systems.

and Zihni Onur Uygun2

PorphobilinogenDeaminase

Specific Two Aptamers

AIV H5N2 Monoclonal Anti-H5

192 State of the Art in Biosensors - General Aspects

Lysozyme and Adenosine Lysozyme and Adenosine

**Table 1.** Comparison of Some Impedimetric Biosensor Systems

Chronic Lymphocytic Leukemia Gene Sequence Mutation

Lipopolysaccaride Layer of *S.*

**6. Conclusion**

**Author details**

Hilmiye Deniz ErtuğruL<sup>1</sup>

1 Ondokuz Mayıs University, Turkey

2 Çanakkale Onsekiz Mart University, Turkey

*marcescens*

Antibody

25-Mer

(PBGD) Gene


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