**Meet the editor**

Dr. Sabine Wislet-Gendebien obtained her PhD from the Center of Cellular and Molecular Neurobiology at the University of Liège under the supervision of Dr. Bernard Rogister and Pr Gustave Moonen. She completed her postdoctoral training at the Center for Research in Neurodegenerative Disorders directed by Professor St George-Hyslop, in Dr. Anurag Tandon's laboratory, at

the university of Toronto. She is currently a Senior Scientist at the GIGA Neurosciences and an Assistant Professor in the Department of Biomedical and Preclinical Sciences, at the University of Liège. Dr Wislet-Gendebien research focuses on cell replacement therapy in neurological disorders, using adult bone marrow stromal cells.

Contents

**Preface VII**

**Brain Injury 3**

Tanja Vogel

Liang-Wei Chen

Adam R. Cole

**Nervous System 37**

**Section 1 TGF-Beta Signaling and Neuronal Fate Decision 1**

Chapter 1 **Role of TGF-β Signaling in Neurogenic Regions After**

Chapter 2 **Insulin/IGF-Signalling in Embryonic and Adult Neural**

**and Dedifferentiation of Neurons 75** Uwe Ueberham and Thomas Arendt

**Section 2 Wnt Signaling and Neuronal Fate Decision 113**

Sonia Villapol, Trevor T. Logan and Aviva J. Symes

Chapter 3 **The Role of Smad Proteins for Development, Differentiation**

Chapter 4 **Wnt Signaling Roles on the Structure and Function of the**

Nibaldo C. Inestrosa and Lorena Varela-Nallar

Chapter 5 **Roles of Wnt/β-Catenin Signaling in Controlling the**

Chapter 6 **Regulation of Cell Fate in the Brain by GSK3 153**

**Proliferation and Differentiation in the Mammalian Central**

**Central Synapses: Involvement in Alzheimer's Disease 115**

**Dopaminergic Neuronal Cell Commitment of Midbrain and Therapeutic Application for Parkinson's Disease 141**
