**Transition State Analogues of Enzymatic Reaction as Potential Drugs**

[51] Kulkarni-Almeida AA, Brahma MK, Padmanabhan P, Mishra PD, Parab RR, Gaik‐ wad NV. Fermentation, Isolation, Structure, and antidiabetic activity of NFAT-133

[52] Lincke T, Behnken S, Ishida K, Roth M, Hertweck C. Closthioamide: an unprecedent‐ ed polythioamide antibiotic from the strictly anaerobic bacterium *Clostridium cellulo‐ lyticum*. Angewandte Chemie International Edition. 2010; 8; 49(11):2011-3. Air, Water

[53] Lee LH, Cheah YK, Sidik SM, Ab Mutalib NS, Tang YT, Lin HP, Hong K. Molecular characterization of Antarctic actinobacteria and screening for antimicrobial metabo‐ lite production. World Journal Microbiology Biotechnology. 2012; 28:2125–2137.

[54] Oskay M, Üsame Tamer A, Azeri C. Antibacterial activity of some actinomycetes iso‐ lated from farming soils of Turkey. African Journal of Biotechnology. 2004; 3 (9):

[55] Ziemert N, Podell S, Penn K, Badger JH, Allen E, Jensen PR. The Natural Product Do‐ main Seeker NaPDoS: A Phylogeny Based Bioinformatic Tool to Classify Secondary Metabolite Gene Diversity. Plos one/www.plosone. org: 2012; 7(3): e34064. 9 pp.

[56] Miyake Y, Ito C, Itoigawa M, Osawa T. Antioxidants produced by *Eurotium herbario‐ rum* of filamentous fungi used for the manufacture of karebushi, dried bonito (Kat‐

[57] Hsuan SL, Kannan MS, Jeyaseelan S, Y. S. Prakash, G. C. Sieck, and S. K. Maheswar‐ an. *Pasteurella haemolytica*A1-Derived Leukotoxin and Endotoxin Induce Intracellular Calcium Elevation in Bovine Alveolar Macrophages by Different Signaling Path‐

suobushi). Bioscience Biotechnology and Biochemistry. 07/2009; 73(6):1323-7.

ways. Infection and Immunity. 1998; 66(6): 2836–2844.

produced by Streptomyces strain PM0324667. AMB Express. 2011; 21;1(1):42.

and Soil: Resources for Drug Discovery http://dx. doi. org/10. 5772/52659.

441-446.

324 Drug Discovery

Karolina Gluza and Pawel Kafarski

Additional information is available at the end of the chapter

http://dx.doi.org/10.5772/52504
