**3. Drug resistance bacteria**

Some Bacteria can innately be resistant to one or more types of antimicrobial compounds and other can be capable of acquired. In actuality, it is well know the factors that provoke mutations in bacteria that create stronger species that are able to survive to the effects of cur‐ rents drugs. Examples of these factors are the unnecessary use of antibiotics by humans, the use in animal feeds in low doses, availability over-the-counter in many countries, misuse by health professionals, patient failure to follow prescribed treatment, antibiotic use in agricul‐ ture, aquaria and family pets, eating raw or undercooked foods.

It can be describe several strategies of antibiotics resistance in different bacterial genera. Pathogens bacteria that have become resistant to the current antibiotic drug are an increas‐ ing public health problem. Some examples of diseases that have become very hard to treat with the current drugs are wound infections, septicemia, tuberculosis, pneumonia, and gon‐ orrhea, to name a few. One part of the problem is that bacteria and other microbes that cause infections are remarkably adaptable and have developed several mechanisms to be immune to antibiotics and other antimicrobial drugs.

Also, it`s been reported that over-prescription and the improper use of antibiotics has led to the generation of antibiotic resistance bacteria that use to be susceptible at those antibiotics [5].
