**4. Conclusion**

Surface plots were generated to describe the relationship between two operating variables and predicted responses.

Methanol and ethanol were confirmed to be superior and were chosen as the extraction solvents of first choice for the PCO and capsaicin under studied process condition. Regarding capsanthin, it is apparent that *n*-hexane offers optimal values with the highest desirability.

Process conditions, i.e. optimal extraction time and temperature with the highest desirability of analytes content of interest, were developed and verified.
