**7. Clinical symptomatology**

Nonspecific clinical signs: (3P-Signs)


8 Neonatal Bacterial Infection

Hypermetabolism

Hyperoxia

**6. Risk factors** 

 Increase in energy consumption Increase in cardiac output

**Maternal Premature Birth Risk Factors** 

 Chorioamnionitis/Endometritis Infection of the Urino-Genital Systems

 Previous child with GBS infection Previous child born with sepsis

Invasive Procedures

Multiple pregnancy

**Neonatal Risk Factors** 

Male sex

 Hypothermia Invasive procedures Artificial feeding Non-insurance fetus

Gestational Age(SGA)

Asphyxia/Resuscitation

Stable intranatal fetal tachycardia

Lack of "Skin-to-skin" contact with mother

Poor sanitary habits of medical personnel.

hour is associated with infection process.[12]

Long-term Hospitalization; Irrational antibiotic therapy

strategies of prophylaxis are precisely based on this data. [11]

**Change of Body Temperature as a Sign of Possible Infection in Neonates** 

 Preterm rupture of the fetus membrane Anhydrous periodgreater than 18 hours

 Febrile temperature greater than38°C (at or after birth) GBS bacteriuria during current pregnancy (>104 cfu/mL) GBS bacterial colonization of the vagina/perineum

Premature neonate less than 37 weeks of gestation, Low birth weight and Small for

It is essential to know the evidence-based risk factors of neonatal infection as modern

The use of a mercury glass thermometer is considered the gold standard for measuring the normal body temperature of neonates – 36.5 – 37.5 C. Sepsis is characterized by arise in temperature or hypothermia. Rise of temperature greater than38C that lasts more than an

**Flow Phase Includes Some Clinical Symptoms:** 

Poor looking

Clinical signs are various and the diversity of symptoms is the result of metabolic and inflammatory processes arisen in case of neonatal sepsis. [12]

Consequently, clinical symptoms of sepsis are nonspecific: They cannot be summarized according to principles: Poor Breathing, Poor Eating and Poor Looking. Out of 10 children with suspected sepsis, the disease will be confirmed in only one.

### **Symptoms of Respiratory Disorders:**


#### **Symptoms of Gastro-intestinal and Neurologic Disorders:**


#### **Symptoms of Cardiovascular and Skin Disorders:**

#### **Cardiovascular:**

Hypotension

