**Definition**

Neonatal sepsis is a clinical syndrome which represents a general reaction to infection. It is characterized by systemic inflammation and general damage of tissues. Clinical definition is based on existing infection and systemic inflammatory response. Neonatal sepsis is diagnosed on the bases of clinical or microbiological data. Neonatal sepsis is an irreversible process which may cause mortality in cases of untimely detection and treatment.

#### **Which symptoms are specific for sepsis in newborns?**


14 Neonatal Bacterial Infection

**CEFOTAXIME** 

**Dosage of Antibiotics: Cefotaxime** 

**Gestational Age (weeks.)** 

Single Dose 50 mg/kg intravenously slowly during 30 minutes *Or I/M*

<sup>≤</sup> 29 0-28

30-36 0-14

37-44 0-7

**Table 4.** Therapeutic guidelines in neonatal infection 2011[11]

necrotic enterocolitis; Subdural empyema; Meningitis

Neofax 2009 Twenty Second Edition [14]

**11. Consultation with parents** 

**Information for Patients** 

**What is Sepsis?** 

Newborn".

**Definition** 

postnatal age of the neonate and it is chosen according to the Neofax guide.[14]

**Postnatal Age (days)** 

> 28

> 14

> 7

≥ 45 All 6

**Complications include the following:** Septic shock; Necrotic tonsillitis enterocolitis, ulcero-

Sepsis – Is the existence of infection in the blood. Sepsis is a serious disease that impacts the whole body. Treatment of Sepsis should be started immediately after diagnosis, because the late start of treatment may endanger life. Sepsis may occur in infants, children and adults as well. Sepsis diagnosed in children less than 1 month old is specified by the term "Sepsis of

Neonatal sepsis is a clinical syndrome which represents a general reaction to infection. It is characterized by systemic inflammation and general damage of tissues. Clinical definition is based on existing infection and systemic inflammatory response. Neonatal

The dosage of antibiotics is relevant to the etiological agent and depends on gestational and

**Interval between Injection (hours)** 

> 12 8

> 12 8

> 12 8


#### **Danger signs:**

#### **When is it necessary to contact the doctor?**

You should contact your pediatrician if your baby has one of above-listed symptoms or looks sick.

#### **Is there a need to conduct laboratory tests on a child?**

**Yes, the doctor will ask:** About the symptoms the baby has, previous deliveries and the baby's status at birth. Observation of child will be conducted and blood analysis of the child will be done including tests known as 'Blood Inoculation'. These tests may determine the existence of infection in the blood.
