**2. Pathogenesis of Chagas' myocarditis**

Milei et al. proposed a combined theory that could explain the pathogenic mechanism in chronic chagasic myocarditis (Milei, et al., 1996a, Storino & Milei, 1994). This theory is based on three ingredients: the parasite, host immune system and fibrosis. These ingredients are proposed as being the primary causative agents of damage on myocardial tissue, conduction system, autonomic ganglia and nerves and microvasculature.
