**6. References**


**2** 

**Therapeutic Keratoplasty** 

Ana Lilia Pérez-Balbuena, Diana Santander-García, Virginia Vanzzini-Zago and Diego Cuevas-Cancino *Hospital Dr. Luis Sánchez Bulnes de la Asociación Para Evitar* 

Keratitis infections caused by bacteria, fungus or *Acanthamoeba* may be the most important reason for visual loss after trachoma and xerophtalmia in undeveloped and developed

Early diagnosis and the availability of the powerful antibiotics give the opportunity of having a better control of the corneal infectious processes, mainly in those of bacteriological

However, the virulence and resistance of some bacteria Hill JC et al 1986, fungi Polack FM et al 1971 and *Acanthamoeba* Blackman HJ 1984 may progress inexorably despite the maximum therapy applied and in those cases the integrity of the ocular globe will be jeopardized and then, it will be necessary to realize a penetrating keratoplasty, by removing, totally of partially, the infectious area in the cornea in the levels where the antibiotics and defense

The tectonic and therapeutic keratoplasty constitute a significant percentage of corneal transplants held in Asia and in some other under developed cities. In Singapore, it was reported a survey in which 13% of all transplants were with therapeutic or tectonic

 In Mexico, it was reported, in a 10 year-period, from 2001 thru 2010, out of the 3240 transplants carried out in the Hospital for the prevention of Blindness, "Asociación para Evitar la Ceguera en Mexico, IAP" Mexico City had a tectonic or therapeutic indication. If we divide the therapeutic indication from the tectonic, the percentage lows down to 2.06%

The therapeutic keratoplasty is a surgical procedure whose indications include the following

a. To solve an infectious keratitis or a maximum conventional refractory inflammatory

b. To reestablish the integral structure of the ocular globe because of the risk of sclera extension, descematocele or corneal perforation (tectonic keratoplasty). In some cases,

**1. Introduction** 

etiology.

**2. Indications** 

circumstances:

treatment.

both situations occur.

countries. Wilhelmus KR. 1998.

mechanisms of the guest, might be effective.

indication Tan DT, Janardhanan P 2008.

**for Microbial Keratitis** 

 *la Ceguera en México I.A.P.* 

 *México D.F.* 

