**8.1 Early-onset complications**

## **8.1.1 Seidel**

This is an avoidable complication if the surgical technique is careful and the wound is well constructed The best way to prevent wound leaks is to ensure meticulous wound apposition at the end of the procedure. Promptly resuturing is recommended if non surgical attempts like patching or contact lens bandage fail to seal the leak. Prolonged contact between the donor cornea and the iris, lens, or IOL may result in irreversible complications and sequel. In our experience resuture was needed in 1, 49% of therapeutic keratoplasty.

Appropriate antimicrobial therapy must be continued postoperatively until the corneal

The general guidelines for postoperative management are shown in (Box 1). Therapy may be guided by histopathological and microbiological evaluation of the excised corneal

Postoperative complications after therapuetic keratoplasty are virtually the same as in other

Depending on the time of onset, complications can be divided in early- onset complications (within 2 weeks) and late-onset complications. The early postoperative period may be complicated with wound leak, shallow anterior chamber, hyphema, anterior uveitis, elevated intraocular pressure, persistent epithelial defect and re- infection of the graft. Late postoperative complications include cataract, glaucoma, graft failure secondary to rejection,

Table 3. Therapeutic keratoplasty Complications of infectious keratitis 2025 cases, during 10 years (2000-2010) in 14.65% cases with therapeutic keratoplasty in advanced process, dates of "Asociación Para Evitar la Ceguera en México Hospital "Dr. Luis Sanchez Bulnes", some

This is an avoidable complication if the surgical technique is careful and the wound is well constructed The best way to prevent wound leaks is to ensure meticulous wound apposition at the end of the procedure. Promptly resuturing is recommended if non surgical attempts like patching or contact lens bandage fail to seal the leak. Prolonged contact between the donor cornea and the iris, lens, or IOL may result in irreversible complications and sequel.

In our experience resuture was needed in 1, 49% of therapeutic keratoplasty.

10.44 1.70

infection or endothelial decompensation and phthisis bulbi. Table 3

COMPLICATION % Corneal Decompesation/ primary failure 37.31 Recidive 31.34 Persistent epithelial defect 23.88 Glaucoma 22.38 Refractory to treatment reyect 7.46 Cataract 7.46 Ptisis bulbi 2.98 Corneal melting 4.47 Seidel 1.49 Retinal detachment or DC 1.49 Cellulitis orbitaria 1.49 Primary failure 26.66

epithelium has healed

**8. Complication** 

Corneal decompensation Flat anterior chamber

patient had one or two complications.

**8.1 Early-onset complications** 

**8.1.1 Seidel** 

situations, except the prevalence is greater.

tissue.
