**Meet the editor**

Dr. Horacio Pérez-Sánchez is currently a researcher at the School of Computer Science of the University of Murcia in the Parallel Computer Architecture Group where he works in several research lines related with the implementation and exploitation of bioinformatics methodologies in parallel architectures and its application to drug discovery problems. He graduated in Theoretical and

Computational Chemistry from the University of Murcia (Spain) in 2000, where he also obtained his Ph.D. degree in 2006, which consisted in the development and implementation of computational methodologies for the study of macromolecular systems. He has performed research in several European Institutions such as the Institute of Structural Biology (CEA, Grenoble, France), where he successfully developed and applied computational methodologies for the prediction and interpretation of macromolecular behavior in solution, and at the Karlsruhe Institute of Technology (Karlsruhe, Germany), where he developed new methodologies for drug discovery and implemented them in parallel architectures such the Cell Broadband Engine, Graphics Processing Units and Supercomputers.

Contents

**Preface IX** 

**Section 2 Sequence Analysis 75** 

**Section 1 Analysis of Biological Networks 1** 

Chapter 2 **Investigation on Nuclear Transport of** 

Chapter 4 **SeqAnt 2012: Recent Developments in** 

**Section 3 High-Performance Computing 105** 

Imre Pechan and Béla Fehér

**Data Integration and Mining 3**  Shubhalaxmi Kher, Jianling Peng, Eve Syrkin Wurtele and Julie Dickerson

Mohd Fakharul Zaman Raja Yahya,

Chapter 3 **Systemic Approach to the Genome Integration Process of Human Lentivirus 55** 

*Trypanosoma brucei***: An** *in silico* **Approach 31** 

Felipe García-Vallejo and Martha Cecilia Domínguez

**Next-Generation Sequencing Annotation 77** 

Chapter 5 **Towards a Hybrid Federated Cloud Platform to Efficiently Execute Bioinformatics Workflows 107** 

Chapter 6 **Hardware Accelerated Molecular Docking: A Survey 133** 

Dhanya Ramachandran and Michael E. Zwick

Roberto Togawa and João Carlos Setubal

Matthew Ezewudo, Promita Bose, Kajari Mondal, Viren Patel,

Hugo Saldanha, Edward Ribeiro, Carlos Borges, Aletéia Araújo, Ricardo Gallon, Maristela Holanda, Maria Emília Walter,

Umi Marshida Abdul Hamid and Farida Zuraina Mohd Yusof

Chapter 1 **Hierarchical Biological Pathway** 
