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**Chapter 6** 

© 2012 Neda et al., licensee InTech. This is an open access chapter distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

© 2012 Neda et al., licensee InTech. This is a paper distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

**Peptide and Amino Acids Separation** 

Paula Sfarloaga, Ioan Grozescu and Adina-Elena Segneanu

about one quarter of prescription drugs contain substances of plant origin.

pharmaceutical and food industries (Busquet et al., 2005 [1]).

these extracts, which show important antitumor activities.

Ion Neda, Paulina Vlazan, Raluca Oana Pop,

Additional information is available at the end of the chapter

http://dx.doi.org/10.5772/51619

**1. Introduction** 

**and Identification from Natural Products** 

The natural extracts of plants are an important source for the identification of new biologically active compounds with possible applications in the pharmaceutical field. Phytotherapy embraces especially the isolation from herbs, of compounds with unique chemical structures, which are considered to be pharmacologically active. Recent statistics show that, on an annual basis, there are identified over 1500 new compounds from different species of plants, and

Although globally there are many studies on natural products, research in this area continues to be of great latent potential, in part due to the existing and still unexploited, potential and perspective development of new opportunities to recovery in major industrial areas and because of their socio-economic impact. A large number of plant extracts that have been used in the traditional medicine have also applications nowadays, both in the

It is known that native Carpathian flora represents about 30% of plant species on the entire European continent. In Romanian, traditional medicine, there are used a number of plants with powerful therapeutic effects, and, as a result, an extensive investigation of their content is necessary. There are many classes of compounds that can be found in an alcoholic, natural extracts: amino acids, peptides, small proteins, phenols, polyphenols, saponins, flavonoids and sugars. Compounds of great interest are the free amino acids and the peptides from

The process of structure elucidation of a natural product involves the determination of many physical-chemical properties: melting point, optical rotation, solubility, absorption, optical rotatory dispersion, circular dichroism, infrared spectroscopy, as well as mass and


**Chapter 6** 
