**Author details**

88 Analytical Chemistry

If we express [RS-

and ionic-strength adjuster.

**List of abbreviations** 

AA L-ascorbic acid cys L-cysteine

we obtain

eq

*K*

H

 

*c*

(RSH)

RSH

] with dissociation constant of RSH,

RS

DA dehydrogenized (oxidised) form of ascorbic acid

EDTA ethylenediaminetetraacetic acid

FISE fluoride ion-selective electrode

FIA flow injection analysis

RSH

In 0.100 mol L–1 perchloric acid, where experiment was performed, (RSH) 1.

*c*

Ag (RSH) (RSH)


eq

*K*

RSH RSH

a, RSH + RSH

H *<sup>K</sup>*

a, RSH

0.100 (RSH) 6.3 10 2.29 10 1 *<sup>c</sup>*

6 1 *c*(RSH) 7.0 10 mol L

This concentration of penicillamine may be estimated as the detection limit for describing experimental conditions. The solution of Ag+ was pumped as a reagent in a two-line flow manifold typically at a concentration of 10-5 mol L–1 with 0.1 mol L–1 perchloric acid as a pH

H

 


*K* H

 

*c* RSH RS RSH

Ag (RSH)

H

9

(29)

(30)

(31)

(32)

2.26 x 10

Njegomir Radić and Lea Kukoc-Modun *Department of Analytical Chemistry, Faculty of Chemistry and Technology, University of Split, Croatia* 

#### **6. References**


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**Chapter 4** 

© 2012 Valcárcel, licensee InTech. This is an open access chapter distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

© 2012 Valcárcel, licensee InTech. This is a paper distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

**Figure 1.** Analytical Chemistry at various interfaces. (1) Internal and interdisciplinary interfaces in the

realm of Chemistry. (2) Interfaces with norms and guides. For details, see text.

**Analytical Chemistry Today and Tomorrow** 

Dealing with Analytical Chemistry in isolation is a gross error [1]. In fact, real advances in Science and Technology —rather than redundancies with a low added value on similar topics— occur at interfaces, which are boundaries, crossroads —rather than barriers between scientific and technical disciplines mutually profiting from their particular approaches and synergistic effects. Figure 1 depicts various types of interfaces involving

Miguel Valcárcel

**1. Introduction** 

Analytical Chemistry.

http://dx.doi.org/10.5772/50497

Additional information is available at the end of the chapter

[41] The Merck Index, Merck Research Laboratories, New York, 1996.
