**Meet the editor**

Professor Dr. Krassimir Metodiev, MD, PhD, DScmed, FUICC, FHMO, FNRH, is the Head, Dept. Preclinical and Clinical Sciences, Medical University, Varna-Bulgaria, with specialties: immunology, microbiology, chemotherapy. He has qualified in Germany, Austria, Slovakia, Italy, Holland, Hungary, USA and has over 220 publications, personal impact factor over 165.00, 6 medical

books. Has served as a guest-professor in: LMU, Munich-Germany; Danube University, Krems-Austria; Radium Hospital/Inst. Cancer Research, Oslo-Norway; Hadassah-Jerusalem, Sheba-Tel Aviv and Rambam-Haifa, Israel. Has been invited speaker and chaired symposia and conferences in over 40 countries. Editor-in-chief of Journal of IMAB; Editor and member of Editorial Board: Intl. J. Immunopathology and Pharmacology, Europ. J. Inflammation, CEJM, J. Antimicrobial Agents, J.ISAO. Referent: UICC (oncoimmunology), NATO Scientific Affairs' Division (bioterrorism). President of IMAB, Secretary General of FESCI, Board member of ISAO, ESAO, EANO, ISAO/IFAO, EUCAST, BS-BIG-CIC. Has honorary positions/titles: Honorary Professor and Doctor of Hadassah-Jerusalem, Radium-Oslo, Chiang Mai-Thailand; Honorary Consul of Israel in Bulgaria.

Contents

**Preface IX** 

Chapter 2 **"Wrapped Up" Vaccines in** 

Chapter 3 **Is Anticancer Vaccine Possible:** 

Yıldız Camcıoğlu

Cleo G. Anastassopoulou

Luis Enrique Jerez Puebla

Chapter 7 **Pattern of Clinical Presentations** 

Chapter 8 **Selective Antibody Deficiency** 

Umezurike Hughes Okafor

Chapter 5 **Chemokine Receptors** 

**Section 1 Immunodeficiency – Immunotherapy 1** 

Winni De Haes, Charlotte Pollard, Guido Vanham and Joanna Rejman

**CD34+ Blood Progenitor Cells 77** 

Mary A. Slatter and Andrew R. Gennery

**the Context of HIV-1 Immunotherapy 27** 

**Experimental Application of Produced mRNA Transfected Dendritic Cells Derived from Enriched** 

Paula Lazarova, Gunnar Kvalheim and Krassimir Metodiev

Chapter 4 **Immunoglobulin Treatment of Immunodeficient Patients 89** 

**Section 2 Immunodeficiency – Mechanisms and Pathophysiology 113** 

**as Therapeutic Targets in HIV Infection 115** 

Chapter 6 **Fungal Infections in Immunosuppressed Patients 149** 

**in Immunocompromised Patient 177** 

**with Normal Immunoglobulins 191** 

Ricardo U. Sorensen, Tammy Harvey and Lily E. Leiva

Chapter 1 **Stem Cell Transplantation for Primary Immunodeficiency 3** 
