**7. XCR1**

The "C" sub-family of chemokine receptors contains only one member: XCR1, also known as GPR5. It is the receptor for chemokines XCL1 and XCL2 formerly, lymphotactin-1 and-2, respectively. This receptor is closely related to the MIP-1 α and RANTES yet to date its expression and the function of its ligand XCL1 remain elusive. However, at least in murine models, XCR1 has been shown to be expressed on CD8+ DCs and that its ligand XCL1 has shown to be a potent and highly specific chemo-attractant for this subset of DCs.
